Thursday, February 27, 2020

Survey letter Research Paper Example | Topics and Well Written Essays - 500 words

Survey letter - Research Paper Example In order to express my heartfelt gratitude, I hereby enclose a gift certificate of MacDonald’s. Please enjoy with my complements. Attached, you will find a brief questionnaire concerning your business, and a self-addressed stamped envelope. Please return the survey no later than (August 15, 2014) so that i can complete my project on time. 3. What are the average net profits of Central Coast Wines in dollars or percent of sales after computing the overhead costs such as rent, administration, and inventory? (Use more than†¦.or less than†¦.in answering). Are these profits for one owner, or do they split between two or more partners? 7. Which brand is your best selling wine, and in what average quantities does it sell, per day, per week, and per year? What level of competition does this brand stand against other competitors’ products in the market – competitive advantage? 10. What chain of distribution does the company use in getting its products to the right market? Does the distribution channel have many intermediaries? Do these intermediaries affect the utility of the product, such as in price, place, and time

Tuesday, February 11, 2020

Epigenetics Research Paper Example | Topics and Well Written Essays - 1000 words - 1

Epigenetics - Research Paper Example Arthur L. Beaudet earned his bachelor’s degree at the College of the Holy Cross. He studied medicine at the Yale University School of Medicine and is currently the professor and chairman of the Department of Molecular and Human Genetics at the Baylor College of Medicine (Arthur L. Beaudet, 2012). This paper aims to provide a summary of the article, along with statements of opinion in regard to some of the aspects tackled in the research. It also seeks to discuss the impact of the article to the study of epigenetics. Finally, it seeks to provide suggestions on how additional research in the subject matter can help in understanding the role of epigenetics on human health. According to Jiang, Bressler, and Beaudet epigenetics is the â€Å"study of stable and heritable (or potentially heritable) changes in gene expression,† which do not result to â€Å"a change in DNA sequence† (2004, p. 479). The two components of gene expression are labile regulation and epigenetic regulation. Jiang, Bressler, and Beaudet (2004) provided historical perspectives about epigenetics. They have further discussed the role of epigenetics to studying the development of human disease. Jiang, Bressler, and Beaudet (2004) have inferred that epigenetics is crucial to the study of human disease which is manifested in genes that is susceptible to genomic imprinting. In genomic imprinting, gene activities are reversibly altered based on the gender of the parent who is transferring the genes which cause â€Å"unequal expression of paternal and maternal alleles for a diploid locus† (Jiang, Bressler, & Beaudet, p. 480). Genetic and epigenetic phenotypes (e.g. uniparental disomy, as well as imprinting defects, appear as epigenetic disease phenotypes) are produced in the event of mutations and epimutations in human imprinted genes. In addition, chromatin structure and remodeling are also influenced by genetic disorders. Genetic